Adjunct Assistant Professor
JICS-UTK /ORNL
Research
Algorithm development, modeling of physical processes, protein structure prediction, molecular kinetics, molecular dynamics, molecular structure, mass spectrometry: database search algorithms, de novo and hybrid methods.
Education
- Postdoctoral training, PMMB program, DNA structure Ph.D., Physics and Astronomy, Rutgers University (1997),elliptical galaxies dynamics.
- M.S., Applied and Mathematical Physics, Moscow Physics and Technology Institute (1989) molecular and chemical physics, plasma physics, and astrophysics.
Publications
Arnold N. D., Fridman T., Day R. M., and Gorin A.A. (2008) Computing P-values for Peptide Identifications in Mass Spectrometry Bioinformatics Research and Applications, Fourth International Symposium, Lecture Notes in Computer Science}, pp 100-109, ISBN 978-3-540-79449-3
Gorin A., Day R.M., Arnold N.D., and Fridman T. (2006) "De Novo algorithms significantly outperform database search in coverage of normal proteins", Proceedings of 54th ASMS Conference on Mass Spectrometry, p. 107, Seattle, Washington, May 28 - June 1, 2006
Gorin A., Day R.M., Fridman T., and Arnold N.D. (2006) "Estimating informational content of tandm mass-spectrometry data", Protein Science, v 15, Suppl 1, p. 149
Day, R.M., Gorin, A., and Fridman, T. (2006) "De Novo Approach for Finding Post Translational Modifications", Experimental Biology 2006 Late-Breaking Abstracts, San Francisco, CA, April 1-5, 2006
Tema Fridman, Vladimir Protopopescu, Greg Hurst, Andrei Borziak and Andrey G orin, "Optimal construction of theoretical spectra for MS/MS spectra identificat ion", OMICS 2005, Vol.9, No.4, p.380-390
Tema Fridman, Vladimir Protopopescu, Greg Hurst, Andrei Borziak and Andrey G orin, "Generating theoretical spectra for peptide identification", METMBS'05 conference proceedings, Las Vegas June 20-23, 2005, p.180-189
Tema Fridman, Jane Razumovskaya, Nathan Verberkmoes, Greg Hurst, Vladimir Protopopescu and Ying Xu, "The probability distribution for a random match between an experimental - theoretical spectral pair in tandem mass spectrometry", JBCB 2005, Vol.3, No.2, p.455-476