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David E. Graham

Staff Scientist

ORNL


Research

David received his Bachelor of Science Degree from Cornell University in 1995 with a major in Biological Sciences and Economics. He received his Masters Degree in 1998 and his PhD in 2000 both from the University of Illinois at Urbana, Champaign, Illinois, with majors in Microbiology. David serves in the role as Group Leader to the Microbial Ecology & Physiology Group. His primary research interests focus on microbial ecology and genomics of environmental organisms.


Education

  • BS: Biological Sciences and Economics - Cornell University (1995)
  • PhD: Microbiology - University of Illinois at Urbana-Champaign, Illinois (2000)

Publications

Graham, DE, 2011, 2-Oxoacid Metabolism in Methanogenic CoM and CoB Biosynthesis, Methods in Enzymology, 494:301-326

Graham, DE, 2010, A new role for coenzyme F-420 in aflatoxin reduction by soil mycobacteria, Molecular Microbiology, 78:3:533-536

Jeyakanthan, J, RM Drevland, DR Gayathri, D Velmurugan, A Shinkai, S Kuramitsu, S Yokoyama, DE Graham. 2010. Substrate Specificity Determinants of the Methanogen Homoaconitase Enzyme: Structure and Function of the Small Subunit. Biochem J.

Graham, DE; Taylor, SM; Wolf, RZ; et al., 2009, Convergent evolution of coenzyme M biosynthesis in the Methanosarcinales: cysteate synthase evolved from an ancestral threonine synthase, Biochemical Journal, 424:467-478

DE Graham, SM Taylor, RZ Wolf, SC Namboori. 2009. Evolution of a cysteic acid synthase from a methanogen threonine synthase enzyme. Biochem J. 424:467-478.

Zhou, L, M Zhao, RZ Wolf, DE Graham, G Georgiou. 2009. Transcriptional regulation of the Escherichia coli gene rraB, encoding a protein inhibitor of RNase E. J. Bacteriol. 191:6665-6674.

Giles, TG, DJ Fisher, DE Graham. 2009. Independent inactivation of arginine decarboxylase genes by nonsense and missense mutations in Chlamydia trachomatis L2 and D strains. BMC Evol. Biol. 9:166.

Boyd, JM, RM Drevland, DM Downs, DE Graham. 2009 Archaeal ApbC/Nbp35 homologs function as iron-sulfur cluster carrier proteins. J. Bacteriol. 191:1490-1497.


Contact Information

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