Igor Joulin

Keywords:

Signal transduction in prokaryotes; novel computational approaches in genomics

Research Area:

High-throughput and high-resolution computational genomics to study evolution, diversity and molecular mechanisms of signal transduction. Evolution of simple prokaryotic organisms to possess sophisticated molecular detectors and transmitters that adjust most of cellular functions in response to changes in the environment.

Description of Research:

Signal transduction in prokaryotes:
We use high-throughput and high-resolution computational genomics to study the evolution, diversity and molecular mechanisms of signal transduction. We are interested in understanding how simple prokaryotic organisms evolved to possess sophisticated molecular detectors and transmitters that adjust most of their cellular functions in response to changes in the environment.

Novel computational approaches in genomics:
We are facing a challenge of how to derive biologically relevant information from completely sequenced genomes. There are many computational tools to mine raw genomic data (development of such tools and their application is called bioinformatics). The question is which tools to use to solve a particular problem? We are trying to answer this question for a number of biological problems related to signal transduction.

Contact Information

Igor Joulin
Bioinformatics
Associate Professor, Microbiology, The University of Tennessee

UT / ORNL
Phone: 865-974-7687
Fax: 865-974-4007

Email: joulineib@ornl.gov

Degrees

PhD: Microbiology - St. Petersburg State University, Russia (1988)

BS/MS: Biology/Biochemistry - Saratov State University, Russia (1983)